Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice

Adjustment of cerebral blood flow (CBF) to neuronal activity via neurovascular coupling (NVC) has an essential role in maintenance of healthy cognitive function. In aging increased oxidative stress and cerebromicrovascular endothelial dysfunction impair NVC, contributing to cognitive decline. There...

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Détails bibliographiques
Publié dans:Redox Biol
Auteurs principaux: Tarantini, Stefano, Valcarcel-Ares, Marta Noa, Toth, Peter, Yabluchanskiy, Andriy, Tucsek, Zsuzsanna, Kiss, Tamas, Hertelendy, Peter, Kinter, Michael, Ballabh, Praveen, Süle, Zoltán, Farkas, Eszter, Baur, Joseph A., Sinclair, David A., Csiszar, Anna, Ungvari, Zoltan
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477631/
https://ncbi.nlm.nih.gov/pubmed/31015147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101192
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