Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice

Adjustment of cerebral blood flow (CBF) to neuronal activity via neurovascular coupling (NVC) has an essential role in maintenance of healthy cognitive function. In aging increased oxidative stress and cerebromicrovascular endothelial dysfunction impair NVC, contributing to cognitive decline. There...

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Pubblicato in:Redox Biol
Autori principali: Tarantini, Stefano, Valcarcel-Ares, Marta Noa, Toth, Peter, Yabluchanskiy, Andriy, Tucsek, Zsuzsanna, Kiss, Tamas, Hertelendy, Peter, Kinter, Michael, Ballabh, Praveen, Süle, Zoltán, Farkas, Eszter, Baur, Joseph A., Sinclair, David A., Csiszar, Anna, Ungvari, Zoltan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477631/
https://ncbi.nlm.nih.gov/pubmed/31015147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101192
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