Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects

Aging-induced structural and functional alterations of the neurovascular unit lead to impairment of neurovascular coupling responses, dysregulation of cerebral blood flow, and increased neuroinflammation, all of which contribute importantly to the pathogenesis of age-related vascular cognitive impai...

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書誌詳細
出版年:GeroScience
主要な著者: Kiss, Tamas, Nyúl-Tóth, Ádám, Balasubramanian, Priya, Tarantini, Stefano, Ahire, Chetan, Yabluchanskiy, Andriy, Csipo, Tamas, Farkas, Eszter, Wren, Jonathan D., Garman, Lori, Csiszar, Anna, Ungvari, Zoltan
フォーマット: Artigo
言語:Inglês
出版事項: Springer International Publishing 2020
主題:
Original Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206476/
https://ncbi.nlm.nih.gov/pubmed/32056076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00165-5
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