Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood

Aging-induced functional and phenotypic alterations of the vasculature (e.g., endothelial dysfunction, oxidative stress) have a central role in morbidity and mortality of older adults. It has become apparent in recent years that cell autonomous mechanisms alone are inadequate to explain all aspects...

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Detalhes bibliográficos
Publicado no:GeroScience
Main Authors: Kiss, Tamas, Tarantini, Stefano, Csipo, Tamas, Balasubramanian, Priya, Nyúl-Tóth, Ádám, Yabluchanskiy, Andriy, Wren, Jonathan D., Garman, Lori, Huffman, Derek M., Csiszar, Anna, Ungvari, Zoltan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205954/
https://ncbi.nlm.nih.gov/pubmed/32172434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00180-6
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