Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects

Aging-induced structural and functional alterations of the neurovascular unit lead to impairment of neurovascular coupling responses, dysregulation of cerebral blood flow, and increased neuroinflammation, all of which contribute importantly to the pathogenesis of age-related vascular cognitive impai...

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Xehetasun bibliografikoak
Argitaratua izan da:GeroScience
Egile Nagusiak: Kiss, Tamas, Nyúl-Tóth, Ádám, Balasubramanian, Priya, Tarantini, Stefano, Ahire, Chetan, Yabluchanskiy, Andriy, Csipo, Tamas, Farkas, Eszter, Wren, Jonathan D., Garman, Lori, Csiszar, Anna, Ungvari, Zoltan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer International Publishing 2020
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206476/
https://ncbi.nlm.nih.gov/pubmed/32056076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00165-5
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