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Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment

Age-related impairment of angiogenesis likely has a critical role in cerebromicrovascular rarefaction and development of vascular cognitive impairment and dementia (VCID) in the elderly. Recently, we demonstrated that aging is associated with NAD(+) depletion in the vasculature and that administrati...

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Dades bibliogràfiques
Publicat a:GeroScience
Autors principals: Kiss, Tamas, Balasubramanian, Priya, Valcarcel-Ares, Marta Noa, Tarantini, Stefano, Yabluchanskiy, Andriy, Csipo, Tamas, Lipecz, Agnes, Reglodi, Dora, Zhang, Xin A., Bari, Ferenc, Farkas, Eszter, Csiszar, Anna, Ungvari, Zoltan
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885080/
https://ncbi.nlm.nih.gov/pubmed/31144244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00074-2
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