Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence

Whole brain irradiation (WBI) is a mainstream therapy for patients with both identifiable brain metastases and prophylaxis for microscopic malignancies. However, it also promotes accelerated senescence in healthy tissues and leads to progressive cognitive dysfunction in up to 50% of tumor patients s...

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Dettagli Bibliografici
Pubblicato in:GeroScience
Autori principali: Ungvari, Zoltan, Tarantini, Stefano, Hertelendy, Peter, Valcarcel-Ares, M. Noa, Fülöp, Gabor A., Logan, Sreemathi, Kiss, Tamas, Farkas, Eszter, Csiszar, Anna, Yabluchanskiy, Andriy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352588/
https://ncbi.nlm.nih.gov/pubmed/28299642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-017-9964-z
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