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Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice

Moment-to-moment adjustment of cerebral blood flow (CBF) to neuronal activity via the homeostatic mechanism known as neurovascular coupling (NVC) has an essential role in maintenance of normal brain function. In advanced age cerebromicrovascular endothelial dysfunction impairs NVC responses, which c...

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Publicado en:GeroScience
Autores principales: Csiszar, Anna, Yabluchanskiy, Andriy, Ungvari, Anna, Ungvari, Zoltan, Tarantini, Stefano
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885076/
https://ncbi.nlm.nih.gov/pubmed/31643012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00111-0
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