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Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice

Moment-to-moment adjustment of cerebral blood flow (CBF) to neuronal activity via the homeostatic mechanism known as neurovascular coupling (NVC) has an essential role in maintenance of normal brain function. In advanced age cerebromicrovascular endothelial dysfunction impairs NVC responses, which c...

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Détails bibliographiques
Publié dans:GeroScience
Auteurs principaux: Csiszar, Anna, Yabluchanskiy, Andriy, Ungvari, Anna, Ungvari, Zoltan, Tarantini, Stefano
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885076/
https://ncbi.nlm.nih.gov/pubmed/31643012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00111-0
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