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Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice

Moment-to-moment adjustment of cerebral blood flow (CBF) to neuronal activity via the homeostatic mechanism known as neurovascular coupling (NVC) has an essential role in maintenance of normal brain function. In advanced age cerebromicrovascular endothelial dysfunction impairs NVC responses, which c...

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Publicado en:GeroScience
Main Authors: Csiszar, Anna, Yabluchanskiy, Andriy, Ungvari, Anna, Ungvari, Zoltan, Tarantini, Stefano
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885076/
https://ncbi.nlm.nih.gov/pubmed/31643012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00111-0
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