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Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice

Moment-to-moment adjustment of cerebral blood flow (CBF) to neuronal activity via the homeostatic mechanism known as neurovascular coupling (NVC) has an essential role in maintenance of normal brain function. In advanced age cerebromicrovascular endothelial dysfunction impairs NVC responses, which c...

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Bibliografische gegevens
Gepubliceerd in:GeroScience
Hoofdauteurs: Csiszar, Anna, Yabluchanskiy, Andriy, Ungvari, Anna, Ungvari, Zoltan, Tarantini, Stefano
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885076/
https://ncbi.nlm.nih.gov/pubmed/31643012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00111-0
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