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New Ligand Binding Function of Human Cerberus and Role of Proteolytic Processing in Regulating Ligand–Receptor Interactions and Antagonist Activity
Cerberus is a key regulator of vertebrate embryogenesis. Its biological function has been studied extensively in frog and mouse embryos. Its ability to bind and antagonize the transforming growth factor-β (TGF-β) family ligand Nodal is well established. Strikingly, the molecular function of Cerberus...
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| Izdano u: | J Mol Biol |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7739268/ https://ncbi.nlm.nih.gov/pubmed/26802359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.01.011 |
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