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Human Cerberus Prevents Nodal-Receptor Binding, Inhibits Nodal Signaling, and Suppresses Nodal-Mediated Phenotypes

The Transforming Growth Factor-ß (TGFß) family ligand Nodal is an essential embryonic morphogen that is associated with progression of breast and other cancers. It has therefore been suggested that Nodal inhibitors could be used to treat breast cancers where Nodal plays a defined role. As secreted a...

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Vydáno v:PLoS One
Hlavní autoři: Aykul, Senem, Ni, Wendi, Mutatu, Washington, Martinez-Hackert, Erik
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300205/
https://ncbi.nlm.nih.gov/pubmed/25603319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114954
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