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Determination of half-maximal inhibitory concentration using biosensor-based protein interaction analysis

The half-maximal inhibitory concentration (IC(50)) is the most widely used and informative measure of a drug’s efficacy. It indicates how much drug is needed to inhibit a biological process by half, thus providing a measure of potency of an antagonist drug in pharmacological research. Most approache...

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Bibliografiske detaljer
Udgivet i:Anal Biochem
Main Authors: Aykul, Senem, Martinez-Hackert, Erik
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955526/
https://ncbi.nlm.nih.gov/pubmed/27365221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2016.06.025
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