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Transforming Growth Factor-β Family Ligands Can Function as Antagonists by Competing for Type II Receptor Binding
Transforming growth factor-β (TGF-β) family ligands are pleiotropic cytokines. Their physiological activities are not determined by a simple coupling of stimulus and response, but depend critically on context, i.e. the interplay of receptors, ligands, and regulators that form the TGF-β signal transd...
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| Veröffentlicht in: | J Biol Chem |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4865925/ https://ncbi.nlm.nih.gov/pubmed/26961869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.713487 |
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