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Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic

Transforming growth factor β (TGF-β) pathways are key determinants of cell fate in animals. Their basic mechanism of action is simple. However, to produce cell-specific responses, TGF-β pathways are heavily regulated by secondary factors, such as membrane-associated EGF-CFC family proteins. Cellular...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Aykul, Senem, Parenti, Anthony, Chu, Kit Yee, Reske, Jake, Floer, Monique, Ralston, Amy, Martinez-Hackert, Erik
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354514/
https://ncbi.nlm.nih.gov/pubmed/28126904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.747501
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