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γ-Secretase Modulatory Proteins: The Guiding Hand Behind the Running Scissors

Described as the “proteasome of the membrane” or the “scissors in the membrane,” γ-secretase has notoriously complicated biology, and even after decades of research, the full extent of its regulatory mechanism remains unclear. γ-Secretase is an intramembrane aspartyl protease complex composed of fou...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Wong, Eitan, Frost, Georgia R., Li, Yue-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7738330/
https://ncbi.nlm.nih.gov/pubmed/33343338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.614690
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