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γ-Secretase Modulatory Proteins: The Guiding Hand Behind the Running Scissors

Described as the “proteasome of the membrane” or the “scissors in the membrane,” γ-secretase has notoriously complicated biology, and even after decades of research, the full extent of its regulatory mechanism remains unclear. γ-Secretase is an intramembrane aspartyl protease complex composed of fou...

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Détails bibliographiques
Publié dans:Front Aging Neurosci
Auteurs principaux: Wong, Eitan, Frost, Georgia R., Li, Yue-Ming
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7738330/
https://ncbi.nlm.nih.gov/pubmed/33343338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.614690
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