Bothrops moojeni L-amino acid oxidase induces apoptosis and epigenetic modulation on Bcr-Abl(+) cells

BACKGROUND: Resistance to apoptosis in chronic myeloid leukemia (CML) is associated with constitutive tyrosine kinase activity of the Bcr-Abl oncoprotein. The deregulated expression of apoptosis-related genes and alteration in epigenetic machinery may also contribute to apoptosis resistance in CML....

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Venom Anim Toxins Incl Trop Dis
Hlavní autoři: Burin, Sandra Mara, Cacemiro, Maira da Costa, Cominal, Juçara Gastaldi, Grandis, Rone Aparecido De, Machado, Ana Rita Thomazela, Donaires, Flavia Sacilotto, Cintra, Adelia Cristina Oliveira, Ambrosio, Luciana, Antunes, Lusânia Maria Greggi, Sampaio, Suely Vilela, de Castro, Fabíola Attié
Médium: Artigo
Jazyk:Inglês
Vydáno: Centro de Estudos de Venenos e Animais Peçonhentos 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737401/
https://ncbi.nlm.nih.gov/pubmed/33354202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1678-9199-JVATITD-2020-0123
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky