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Antitumor potential of the myotoxin BthTX-I from Bothrops jararacussu snake venom: evaluation of cell cycle alterations and death mechanisms induced in tumor cell lines

BACKGROUND: Phospholipases A(2) (PLA(2)s) are abundant components of snake venoms that have been extensively studied due to their pharmacological and pathophysiological effects on living organisms. This study aimed to assess the antitumor potential of BthTX-I, a basic myotoxic PLA(2) isolated from B...

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Bibliographische Detailangaben
Veröffentlicht in:J Venom Anim Toxins Incl Trop Dis
Hauptverfasser: Prinholato da Silva, Cássio, Costa, Tássia R., Paiva, Raquel M. Alves, Cintra, Adélia C. O., Menaldo, Danilo L., Antunes, Lusânia M. Greggi, Sampaio, Suely V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632473/
https://ncbi.nlm.nih.gov/pubmed/26539212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40409-015-0044-5
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