Translation-Focused Approaches to GPCR Drug Discovery for Cognitive Impairments Associated with Schizophrenia

[Image: see text] There are no effective therapeutics for cognitive impairments associated with schizophrenia (CIAS), which includes deficits in executive functions (working memory and cognitive flexibility) and episodic memory. Compounds that have entered clinical trials are inadequate in terms of...

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Bibliographic Details
Published in:ACS Pharmacol Transl Sci
Main Authors: Hatzipantelis, Cassandra J., Langiu, Monica, Vandekolk, Teresa H., Pierce, Tracie L., Nithianantharajah, Jess, Stewart, Gregory D., Langmead, Christopher J.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2020
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737210/
https://ncbi.nlm.nih.gov/pubmed/33344888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00117
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