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Translation-Focused Approaches to GPCR Drug Discovery for Cognitive Impairments Associated with Schizophrenia

[Image: see text] There are no effective therapeutics for cognitive impairments associated with schizophrenia (CIAS), which includes deficits in executive functions (working memory and cognitive flexibility) and episodic memory. Compounds that have entered clinical trials are inadequate in terms of...

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Библиографические подробности
Опубликовано в: :ACS Pharmacol Transl Sci
Главные авторы: Hatzipantelis, Cassandra J., Langiu, Monica, Vandekolk, Teresa H., Pierce, Tracie L., Nithianantharajah, Jess, Stewart, Gregory D., Langmead, Christopher J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2020
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737210/
https://ncbi.nlm.nih.gov/pubmed/33344888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00117
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