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Translation-Focused Approaches to GPCR Drug Discovery for Cognitive Impairments Associated with Schizophrenia

[Image: see text] There are no effective therapeutics for cognitive impairments associated with schizophrenia (CIAS), which includes deficits in executive functions (working memory and cognitive flexibility) and episodic memory. Compounds that have entered clinical trials are inadequate in terms of...

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Detalhes bibliográficos
Publicado no:ACS Pharmacol Transl Sci
Main Authors: Hatzipantelis, Cassandra J., Langiu, Monica, Vandekolk, Teresa H., Pierce, Tracie L., Nithianantharajah, Jess, Stewart, Gregory D., Langmead, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737210/
https://ncbi.nlm.nih.gov/pubmed/33344888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00117
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