RedEx: a method for seamless DNA insertion and deletion in large multimodular polyketide synthase gene clusters

Biosynthesis reprograming is an important way to diversify chemical structures. The large repetitive DNA sequences existing in polyketide synthase genes make seamless DNA manipulation of the polyketide biosynthetic gene clusters extremely challenging. In this study, to replace the ethyl group attach...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Song, Chaoyi, Luan, Ji, Li, Ruijuan, Jiang, Chanjuan, Hou, Yu, Cui, Qingwen, Cui, Tianqi, Tan, Long, Ma, Zaichao, Tang, Ya-Jie, Stewart, A Francis, Fu, Jun, Zhang, Youming, Wang, Hailong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2020
Aiheet:
Methods Online
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736807/
https://ncbi.nlm.nih.gov/pubmed/33119745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa956
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