Improving the Predictive Value of Prion Inactivation Validation Methods to Minimize the Risks of Iatrogenic Transmission With Medical Instruments

Prions are pathogenic infectious agents responsible for fatal, incurable neurodegenerative diseases in animals and humans. Prions are composed exclusively of an aggregated and misfolded form (PrP(Sc)) of the cellular prion protein (PrP(C)). During the propagation of the disease, PrP(Sc) recruits and...

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Bibliographische Detailangaben
Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Moudjou, Mohammed, Castille, Johan, Passet, Bruno, Herzog, Laetitia, Reine, Fabienne, Vilotte, Jean-Luc, Rezaei, Human, Béringue, Vincent, Igel-Egalon, Angélique
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Bioengineering and Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736614/
https://ncbi.nlm.nih.gov/pubmed/33335894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.591024
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