Improving the Predictive Value of Prion Inactivation Validation Methods to Minimize the Risks of Iatrogenic Transmission With Medical Instruments

Prions are pathogenic infectious agents responsible for fatal, incurable neurodegenerative diseases in animals and humans. Prions are composed exclusively of an aggregated and misfolded form (PrP(Sc)) of the cellular prion protein (PrP(C)). During the propagation of the disease, PrP(Sc) recruits and...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Moudjou, Mohammed, Castille, Johan, Passet, Bruno, Herzog, Laetitia, Reine, Fabienne, Vilotte, Jean-Luc, Rezaei, Human, Béringue, Vincent, Igel-Egalon, Angélique
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736614/
https://ncbi.nlm.nih.gov/pubmed/33335894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.591024
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