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NCOA4 is regulated by HIF and mediates mobilization of murine hepatic iron stores after blood loss

The mechanisms by which phlebotomy promotes the mobilization of hepatic iron stores are not well understood. NCOA4 (nuclear receptor coactivator 4) is a widely expressed intracellular protein previously shown to mediate the autophagic degradation of ferritin. Here, we investigate a local requirement...

詳細記述

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書誌詳細
出版年:Blood
主要な著者: Li, Xiuqi, Lozovatsky, Larisa, Sukumaran, Abitha, Gonzalez, Luis, Jain, Anisha, Liu, Dong, Ayala-Lopez, Nadia, Finberg, Karin E.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735158/
https://ncbi.nlm.nih.gov/pubmed/32659785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020006321
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