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Fetal liver hepcidin secures iron stores in utero

In the adult, the liver-derived hormone hepcidin (HAMP) controls systemic iron levels by blocking the iron-exporting protein ferroportin (FPN) in the gut and spleen, the sites of iron absorption and recycling, respectively. Impaired HAMP expression or FPN responsiveness to HAMP result in iron overlo...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Kämmerer, Lara, Mohammad, Goran, Wolna, Magda, Robbins, Peter A., Lakhal-Littleton, Samira
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515687/
https://ncbi.nlm.nih.gov/pubmed/32542311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003907
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