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An essential cell-autonomous role for hepcidin in cardiac iron homeostasis
Hepcidin is the master regulator of systemic iron homeostasis. Derived primarily from the liver, it inhibits the iron exporter ferroportin in the gut and spleen, the sites of iron absorption and recycling respectively. Recently, we demonstrated that ferroportin is also found in cardiomyocytes, and t...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5176354/ https://ncbi.nlm.nih.gov/pubmed/27897970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19804 |
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