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An essential cell-autonomous role for hepcidin in cardiac iron homeostasis
Hepcidin is the master regulator of systemic iron homeostasis. Derived primarily from the liver, it inhibits the iron exporter ferroportin in the gut and spleen, the sites of iron absorption and recycling respectively. Recently, we demonstrated that ferroportin is also found in cardiomyocytes, and t...
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| Pubblicato in: | eLife |
|---|---|
| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5176354/ https://ncbi.nlm.nih.gov/pubmed/27897970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19804 |
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