Induced Disruption of the Iron-Regulatory Hormone Hepcidin Inhibits Acute Inflammatory Hypoferraemia

Withdrawal of iron from serum (hypoferraemia) is a conserved innate immune antimicrobial strategy that can withhold this critical nutrient from invading pathogens, impairing their growth. Hepcidin (Hamp1) is the master regulator of iron and its expression is induced by inflammation. Mice lacking Ham...

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Pubblicato in:J Innate Immun
Autori principali: Armitage, Andrew E., Lim, Pei Jin, Frost, Joe N., Pasricha, Sant-Rayn, Soilleux, Elizabeth J., Evans, Emma, Morovat, Alireza, Santos, Ana, Diaz, Rebeca, Biggs, Daniel, Davies, Benjamin, Gileadi, Uzi, Robbins, Peter A., Lakhal-Littleton, Samira, Drakesmith, Hal
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322583/
https://ncbi.nlm.nih.gov/pubmed/27423740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000447713
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