Decreased Hepcidin Levels Are Associated with Low Steady-state Hemoglobin in Children With Sickle Cell Disease in Tanzania

BACKGROUND: The contribution of hepcidin as a regulator of iron metabolism & erythropoiesis on the severity of anemia in sickle cell disease (SCD) remains poorly characterized, especially in Sub-Saharan African populations. The aims of the study were to determine if hepcidin is associated with s...

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Udgivet i:EBioMedicine
Main Authors: Lee, Nathaniel, Makani, Julie, Tluway, Furahini, Makubi, Abel, Armitage, Andrew E., Pasricha, Sant-Rayn, Drakesmith, Hal, Prentice, Andrew M., Cox, Sharon E.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6116423/
https://ncbi.nlm.nih.gov/pubmed/30056060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.07.024
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