Hepcidin is suppressed by erythropoiesis in hemoglobin E β-thalassemia and β-thalassemia trait

Hemoglobin E (HbE) β-thalassemia is the most common severe thalassemia syndrome across Asia, and millions of people are carriers. Clinical heterogeneity in HbE β-thalassemia is incompletely explained by genotype, and the interaction of phenotypic variation with hepcidin is unknown. The effect of tha...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Blood
Päätekijät: Jones, Emma, Pasricha, Sant-Rayn, Allen, Angela, Evans, Patricia, Fisher, Chris A., Wray, Katherine, Premawardhena, Anuja, Bandara, Dyananda, Perera, Ashok, Webster, Craig, Sturges, Pamela, Olivieri, Nancy F., St. Pierre, Timothy, Armitage, Andrew E., Porter, John B., Weatherall, David J., Drakesmith, Hal
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2015
Aiheet:
Red Cells, Iron, and Erythropoiesis
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321326/
https://ncbi.nlm.nih.gov/pubmed/25519750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-606491
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