Methemoglobinemia and ascorbate deficiency in hemoglobin E β thalassemia: metabolic and clinical implications

During investigations of the phenotypic diversity of hemoglobin (Hb) E β thalassemia, a patient was encountered with persistently high levels of methemoglobin associated with a left-shift in the oxygen dissociation curve, profound ascorbate deficiency, and clinical features of scurvy; these abnormal...

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Detalhes bibliográficos
Main Authors: Allen, Angela, Fisher, Christopher, Premawardhena, Anuja, Bandara, Dayananda, Perera, Ashok, Allen, Stephen, St Pierre, Timothy, Olivieri, Nancy, Weatherall, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Plenary Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471769/
https://ncbi.nlm.nih.gov/pubmed/22885163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-435875
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