Blockage of AEP attenuates TBI-induced tau hyperphosphorylation and cognitive impairments in rats

Traumatic brain injury (TBI) is regarded as a high-risk factor for Alzheimer's disease (AD). Asparaginyl endopeptidase (AEP), a lysosomal cysteine protease involved in AD pathogenesis, is normally activated under acidic conditions and also in TBI. However, both the molecular mechanism underlyin...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Liu, Yi, Guo, Cuiping, Ding, Yi, Long, Xiaobing, Li, Wensheng, Ke, Dan, Wang, Qun, Liu, Rong, Wang, Jian-Zhi, Zhang, Huaqiu, Wang, Xiaochuan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732271/
https://ncbi.nlm.nih.gov/pubmed/33040048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103841
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker