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Tau-Induced Ca(2+)/Calmodulin-Dependent Protein Kinase-IV Activation Aggravates Nuclear Tau Hyperphosphorylation
Hyperphosphorylated tau is the major protein component of neurofibrillary tangles in the brains of patients with Alzheimer’s disease (AD). However, the mechanism underlying tau hyperphosphorylation is not fully understood. Here, we demonstrated that exogenously expressed wild-type human tau40 was de...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Neurosci Bull |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Springer Singapore
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5856708/ https://ncbi.nlm.nih.gov/pubmed/28646348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-017-0148-8 |
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