Loading...
Selective Binding of Cyclodextrins with Leflunomide and Its Pharmacologically Active Metabolite Teriflunomide
The selectivity of encapsulation of leflunomide and teriflunomide by native α-, β- and γ-cyclodextrins was investigated through (1)H NMR and molecular modeling. Thermodynamic analysis revealed the main driving forces involved in the binding. For α-cyclodextrin, the partial encapsulation was obtained...
Saved in:
| Published in: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2020
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7730839/ https://ncbi.nlm.nih.gov/pubmed/33265979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239102 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|