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From Leflunomide to Teriflunomide: Drug Development and Immuno-suppressive Oral Drugs in the Treatment of Multiple Sclerosis

BACKGROUND: Immunosuppressive drugs have been used in the treatment of multiple sclerosis (MS) for a long time. Today, orally available second generation immunosuppressive agents have been approved or are filed for licensing as MS therapeutics. Due to semi-selective targeting of cellular processes,...

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Pubblicato in:Curr Neuropharmacol
Autori principali: Aly, Lilian, Hemmer, Bernhard, Korn, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Bentham Science Publishers 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652031/
https://ncbi.nlm.nih.gov/pubmed/27928949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X14666161208151525
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