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On the interactions of leflunomide and teriflunomide within receptor cavity — NMR studies and energy calculations
Leflunomide is a disease-modifying antirheumatic drug with antiinflammatory and immunosuppressive activity used for the treatment of psoriatic and rheumatoid arthritis. It undergoes rapid metabolization to teriflunomide, a metabolite that is responsible for the biological activity of leflunomide. Co...
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| Vydáno v: | J Mol Model |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Springer Berlin Heidelberg
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4391734/ https://ncbi.nlm.nih.gov/pubmed/25851105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-015-2643-z |
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