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Inhibition of the NLRP3 inflammasome by HSP90 inhibitors

Excessive and dysregulated inflammation is known to contribute to disease progression. HSP90 is an intracellular chaperone known to regulate inflammatory processes including the NLRP3 inflammasome and secretion of the pro‐inflammatory cytokine interleukin(IL)‐1β. Here, primarily using an in vitro in...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Nizami, Sohaib, Arunasalam, Kanisa, Green, Jack, Cook, James, Lawrence, Catherine B., Zarganes‐Tzitzikas, Tryfon, Davis, John B., Di Daniel, Elena, Brough, David
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730016/
https://ncbi.nlm.nih.gov/pubmed/32954500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13267
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