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Unravelling the intricate cooperativity of subunit gating in P2X2 ion channels
Ionotropic purinergic (P2X) receptors are trimeric channels that are activated by the binding of ATP. They are involved in multiple physiological functions, including synaptic transmission, pain and inflammation. The mechanism of activation is still elusive. Here we kinetically unraveled and quantif...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7729398/ https://ncbi.nlm.nih.gov/pubmed/33303878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78672-w |
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