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Unraveling Subunit Cooperativity in Homotetrameric HCN2 Channels
In a multimeric receptor protein, the binding of a ligand can modulate the binding of a succeeding ligand. This phenomenon, called cooperativity, is caused by the interaction of the receptor subunits. By using a complex Markovian model and a set of parameters determined previously, we analyzed how t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491687/ https://ncbi.nlm.nih.gov/pubmed/23199914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.09.024 |
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