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Unravelling the intricate cooperativity of subunit gating in P2X2 ion channels
Ionotropic purinergic (P2X) receptors are trimeric channels that are activated by the binding of ATP. They are involved in multiple physiological functions, including synaptic transmission, pain and inflammation. The mechanism of activation is still elusive. Here we kinetically unraveled and quantif...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7729398/ https://ncbi.nlm.nih.gov/pubmed/33303878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78672-w |
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