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Quantifying the cooperative subunit action in a multimeric membrane receptor

In multimeric membrane receptors the cooperative action of the subunits prevents exact knowledge about the operation and the interaction of the individual subunits. We propose a method that permits quantification of ligand binding to and activation effects of the individual binding sites in a multim...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wongsamitkul, Nisa, Nache, Vasilica, Eick, Thomas, Hummert, Sabine, Schulz, Eckhard, Schmauder, Ralf, Schirmeyer, Jana, Zimmer, Thomas, Benndorf, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746656/
https://ncbi.nlm.nih.gov/pubmed/26858151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20974
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