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Hysteresis of ligand binding in CNGA2 ion channels

Tetrameric cyclic nucleotide-gated (CNG) channels mediate receptor potentials in olfaction and vision. The channels are activated by the binding of cyclic nucleotides to a binding domain embedded in the C terminus of each subunit. Here using a fluorescent cGMP derivative (fcGMP), we show for homotet...

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Bibliografiske detaljer
Main Authors: Nache, Vasilica, Eick, Thomas, Schulz, Eckhard, Schmauder, Ralf, Benndorf, Klaus
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868267/
https://ncbi.nlm.nih.gov/pubmed/24287615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3866
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