Thermodynamics of Activation Gating in Olfactory-Type Cyclic Nucleotide-Gated (CNGA2) Channels

Olfactory-type cyclic nucleotide-gated (CNG) ion channels open by the binding of cyclic nucleotides to a binding domain in the C-terminus. Employing the Eyring rate theory, we performed a thermodynamic analysis of the activation gating in homotetrameric CNGA2 channels. Lowering the temperature shift...

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Detalhes bibliográficos
Main Authors: Nache, Vasilica, Kusch, Jana, Biskup, Christoph, Schulz, Eckhard, Zimmer, Thomas, Hagen, Volker, Benndorf, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Channels, Receptors, and Electrical Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527250/
https://ncbi.nlm.nih.gov/pubmed/18567637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.129718
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