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Gating of Cyclic Nucleotide-Gated (CNGA1) Channels by cGMP Jumps and Depolarizing Voltage Steps

We expressed rod-type homotetrameric cyclic nucleotide-gated (CNGA1) channels in Xenopus oocytes and studied activation by photolysis-induced jumps of the 3′,5′-cyclic guanosine monophosphate (cGMP) concentration and by voltage steps. cGMP jumps to increasing concentrations up to the EC(50) value of...

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Detalhes bibliográficos
Main Authors: Nache, Vasilica, Kusch, Jana, Hagen, Volker, Benndorf, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1432111/
https://ncbi.nlm.nih.gov/pubmed/16473910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.078667
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