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Nature-inspired remodeling of (aza)indoles to meta-aminoaryl nicotinates for late-stage conjugation of vitamin B(3) to (hetero)arylamines

Despite the availability of numerous routes to substituted nicotinates based on the Bohlmann–Rahtz pyridine synthesis, the existing methods have several limitations, such as the inevitable ortho-substitutions and the inability to conjugate vitamin B(3) to other pharmaceutical agents. Inspired by the...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Varun, Begur Vasanthkumar, Vaithegi, Kannan, Yi, Sihyeong, Park, Seung Bum
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726565/
https://ncbi.nlm.nih.gov/pubmed/33298909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19610-2
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