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A Brief Overview of Two Major Strategies in Diversity-Oriented Synthesis: Build/Couple/Pair and Ring-Distortion

In the interdisciplinary research field of chemical biology and drug discovery, diversity-oriented synthesis (DOS) has become indispensable in the construction of novel small-molecule libraries rich in skeletal and stereochemical diversity. DOS aims to populate the unexplored chemical space with new...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Yi, Sihyeong, Varun, Begur Vasanthkumar, Choi, Yoona, Park, Seung Bum
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204370/
https://ncbi.nlm.nih.gov/pubmed/30406085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00507
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