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Nature-inspired remodeling of (aza)indoles to meta-aminoaryl nicotinates for late-stage conjugation of vitamin B(3) to (hetero)arylamines

Despite the availability of numerous routes to substituted nicotinates based on the Bohlmann–Rahtz pyridine synthesis, the existing methods have several limitations, such as the inevitable ortho-substitutions and the inability to conjugate vitamin B(3) to other pharmaceutical agents. Inspired by the...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Varun, Begur Vasanthkumar, Vaithegi, Kannan, Yi, Sihyeong, Park, Seung Bum
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726565/
https://ncbi.nlm.nih.gov/pubmed/33298909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19610-2
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