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Enantioselective N–alkylation of Indoles via an Intermolecular Aza-Wacker-Type Reaction
The development of an intermolecular and enantioselective aza-Wacker reaction is described. Using indoles as the N-source, a selection of alkenols as the coupling partner enables selective β-hydride elimination towards the alcohol. This strategy preserves the newly formed stereocenter by preventing...
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| Yayımlandı: | J Am Chem Soc |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6583780/ https://ncbi.nlm.nih.gov/pubmed/31117643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b01476 |
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