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Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease

Interleukin (IL)-38 belongs to the IL-1 family and is part of the IL-36 subfamily due to its binding to the IL-36 Receptor (IL-1R6). In the current study, we assessed the anti-inflammatory properties of IL-38 in murine models of arthritis and systemic inflammation. First, the anti-inflammatory prope...

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Bibliografski detalji
Izdano u:Cytokine
Glavni autori: de Graaf, Dennis M., Maas, Ralph J.A., Smeekens, Sanne P., Eisenmesser, Elan, Redzic, Jasmina S., Helsen, Monique M., Powers, Nicholas E., Li, Suzhao, Kalabokis, Vassili, Gresnigt, Mark S., Joosten, Leo A.B., Dinarello, Charles A., van de Veerdonk, Frank L.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725974/
https://ncbi.nlm.nih.gov/pubmed/33128926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2020.155334
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