PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis

di Powers, Nicholas E., Swartzwelter, Benjamin, Marchetti, Carlo, de Graaf, Dennis M., Lerchner, Alexandra, Schlapschy, Martin, Datar, Rajiv, Binder, Uli, Edwards, Carl K., Skerra, Arne, Dinarello, Charles A.
Pubblicato in J Biol Chem (2020)

A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling

di Li, Suzhao, Jiang, Liqiong, Beckmann, Karsten, Højen, Jesper Falkesgaard, Pessara, Ulrich, Powers, Nicholas E., de Graaf, Dennis M., Azam, Tania, Lindenberger, Jared, Eisenmesser, Elan Z., Fischer, Stephan, Dinarello, Charles A.
Pubblicato in J Biol Chem (2021)

Metabolic Reprogramming of Mouse Bone Marrow Derived Macrophages Following Erythrophagocytosis

di Catala, Alexis, Youssef, Lyla A., Reisz, Julie A., Dzieciatkowska, Monika, Powers, Nicholas E., Marchetti, Carlo, Karafin, Matthew, Zimring, James C., Hudson, Krystalyn E., Hansen, Kirk C., Spitalnik, Steven L., D’Alessandro, Angelo
Pubblicato in Front Physiol (2020)

Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease

di de Graaf, Dennis M., Maas, Ralph J.A., Smeekens, Sanne P., Eisenmesser, Elan, Redzic, Jasmina S., Helsen, Monique M., Powers, Nicholas E., Li, Suzhao, Kalabokis, Vassili, Gresnigt, Mark S., Joosten, Leo A.B., Dinarello, Charles A., van de Veerdonk, Frank L.
Pubblicato in Cytokine (2020)

Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion

di Tengesdal, Isak W., Menon, Dinoop R., Osborne, Douglas G., Neff, Charles P., Powers, Nicholas E., Gamboni, Fabia, Mauro, Adolfo G., D’Alessandro, Angelo, Stefanoni, Davide, Henen, Morkos A., Mills, Taylor S., De Graaf, Dennis M., Azam, Tania, Vogeli, Beat, Palmer, Brent E., Pietras, Eric M., DeGregori, James, Tan, Aik-Choon, Joosten, Leo A. B., Fujita, Mayumi, Dinarello, Charles A., Marchetti, Carlo
Pubblicato in Proc Natl Acad Sci U S A (2021)