PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis

অনুযায়ী Powers, Nicholas E., Swartzwelter, Benjamin, Marchetti, Carlo, de Graaf, Dennis M., Lerchner, Alexandra, Schlapschy, Martin, Datar, Rajiv, Binder, Uli, Edwards, Carl K., Skerra, Arne, Dinarello, Charles A.
প্রকাশিত J Biol Chem (2020)

A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling

অনুযায়ী Li, Suzhao, Jiang, Liqiong, Beckmann, Karsten, Højen, Jesper Falkesgaard, Pessara, Ulrich, Powers, Nicholas E., de Graaf, Dennis M., Azam, Tania, Lindenberger, Jared, Eisenmesser, Elan Z., Fischer, Stephan, Dinarello, Charles A.
প্রকাশিত J Biol Chem (2021)

IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease

অনুযায়ী Højen, Jesper Falkesgaard, Vindvad Kristensen, Marie Louise, McKee, Amy S., Wade, Megan Taylor, Azam, Tania, Lunding, Lars P., de Graaf, Dennis M., Swartzwelter, Benjamin J., Wegmann, Michael, Tolstrup, Martin, Beckman, Karsten, Fujita, Mayumi, Fischer, Stephan, Dinarello, Charles A.
প্রকাশিত Nat Immunol (2019)

Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease

অনুযায়ী de Graaf, Dennis M., Maas, Ralph J.A., Smeekens, Sanne P., Eisenmesser, Elan, Redzic, Jasmina S., Helsen, Monique M., Powers, Nicholas E., Li, Suzhao, Kalabokis, Vassili, Gresnigt, Mark S., Joosten, Leo A.B., Dinarello, Charles A., van de Veerdonk, Frank L.
প্রকাশিত Cytokine (2020)

Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects

অনুযায়ী de Graaf, Dennis M., Jaeger, Martin, van den Munckhof, Inge C. L., ter Horst, Rob, Schraa, Kiki, Zwaag, Jelle, Kox, Matthijs, Fujita, Mayumi, Yamauchi, Takeshi, Mercurio, Laura, Madonna, Stefania, Rutten, Joost H.W., de Graaf, Jacqueline, Riksen, Niels P., van de Veerdonk, Frank L., Netea, Mihai G., Joosten, Leo A.B., Dinarello, Charles A.
প্রকাশিত Eur J Immunol (2020)

Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion

অনুযায়ী Tengesdal, Isak W., Menon, Dinoop R., Osborne, Douglas G., Neff, Charles P., Powers, Nicholas E., Gamboni, Fabia, Mauro, Adolfo G., D’Alessandro, Angelo, Stefanoni, Davide, Henen, Morkos A., Mills, Taylor S., De Graaf, Dennis M., Azam, Tania, Vogeli, Beat, Palmer, Brent E., Pietras, Eric M., DeGregori, James, Tan, Aik-Choon, Joosten, Leo A. B., Fujita, Mayumi, Dinarello, Charles A., Marchetti, Carlo
প্রকাশিত Proc Natl Acad Sci U S A (2021)